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Upon administration, PT-141 binds to these receptors, particularly the melanocortin 4 receptor (MC4R), which plays a crucial role in regulating sexual function and behaviour

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Although enterocytes are the major cell type responsible for lipid uptake, chylomicron assembly, and secretion of TRLs (31), loss of enterocyte DPP-4 in Dpp4 Gut/ mice does not perturb lipid tolerance in RC-fed mice